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Table 1 List of default attributes included in EpiGRAPH

From: EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data

 

Total number of attributes

 

Attribute groups

hg18

hg17

mm9

panTro2

galGal3

Attributes (examples)

DNA sequence

178

178

178

178

178

Frequency of 'TATA' pattern, cytosine content, CpG frequency

DNA structure

21

21

21

21

21

Predicted DNA helix twist, predicted solvent accessibility

Repetitive DNA

95

95

91

94

94

Overlap with Alu elements, LINEs and tandem repeats

Chromosome organization

18

29

15

-

-

Overlap with chromosomal bands and isochors

Evolutionary history

94

101

-

-

86

Overlap with evolutionarily conserved regions

Population variation

75

75

-

-

-

SNP density and overlap with specific SNP types (for example, non-synonymous exonic or splice site)

Genes

37

60

20

10

10

Overlap with annotated genes, pseudogenes and predicted microRNA genes

Regulatory regions

249

259

5

5

5

Overlap with CpG islands and predicted transcription factor binding sites

Transcriptome

49

65

9

9

9

Overlap with ESTs and mRNA sequences

Epigenome and chromatin structure

80

17

114

-

-

Overlap with ChIP-seq tags indicating enrichment for specific histone modifications

Sum

896

900

453

317

403

 
  1. This table summarizes the collection of default attributes that are currently included in EpiGRAPH. Due to different degrees of annotation, the numbers differ between the genomes of human (hg18 and hg17), mouse (mm9), chimp (panTro2) and chicken (galGal3). EST, expressed sequence tag; SNP, single nucleotide polymorphism.