From: Non-imprinted allele-specific DNA methylation on human autosomes
 | Genes and amplicons | |||||
---|---|---|---|---|---|---|
 | C21orf81 | HSF2BP | RIPK4 | CBR1 | ||
 | 23_1 | 23_2 | 262 | 232 | 176_1 | 176_2 |
Length (bp) | 370 | 426 | 400 | 241 | 302 | 476 |
CpG sites | 31 | 26 | 42 | 25 | 31 | 44 |
SNP (strand) dbsnp build 129 | A/C (-) rs2297246 | A/C (+) rs56270809 | A/G (-) rs2838343 | A/G (+) rs55860816 | del/no del (+) rs41563015 | C/G (+) rs25678 |
Individuals studied | 38 | 19 | 33 | 36 | 21 | 21 |
Individuals with SNP | 17 | 8 | 20 | 11 | 1 | 8 |
Individuals with SNP and ASM | 8 | 7 | 19 | 3 | 1 | 1 |
Coupling of ASM and genotype | Always: C hyper- methylated | Always: C hyper- methylated | 18 cases: G hyper- methylated in right part of amplicon | Always: G hyper- methylated | Always: del hyper- methylated | Always: C hyper- methylated |
 |  |  | 1 case: A hyper- methylated in left part of amplicon |  |  |  |
Average allelic methylation difference in ASM cases | 53% | 60% | 54% (G hyper- methylated), 64% (A hyper- methylated) | 39% | 50% | 60% |
Individuals with SNP but without ASM | 9 | 1 | 1 | 8 | 0 | 7 |
Individuals without SNP | 21 | 11 | 13 | 25 | 20 | 13 |