Skip to main content
Figure 4 | Genome Biology

Figure 4

From: Non-imprinted allele-specific DNA methylation on human autosomes

Figure 4

ASM of amplicon 232. (a) Example of ASM of amplicon 232. The figure shows the position of the amplicon in UCSC genome browser, the positions of the SNP (dbsnp rs55860816) used to discriminate alleles, and the allelic methylation, basically as described in the legend to Figure 2a. The correlation of the SNP in this amplicon (dbsnp rs55860816) and a SNP (rs6586238) in the first exon of the gene as identified by sequencing of genomic DNA is schematically shown in the lower part of the figure. SNP (rs6586238) was used to discriminate alleles in gene expression analysis. Sequencing of cDNA showed that the gene is biallelically expressed in leukocytes. (b) Compilation of results from all heterozygous individuals. For further details see the legend to Figure 2b. (c) Methylation level of each allele from all heterozygous individuals. The original methylation patterns of all samples with ASM are shown in Additional file 7.

Back to article page