Skip to main content

Table 3 Features of variable internal tandem repeats present in paralogs of the human morpheus gene

From: Tandem repeats modify the structure of human genes hosted in segmental duplications

    ITRs in genome     ITRs in mRNA
Group ID Genomic locus of exon 8 Exon length (bp) Type1 Type2 CNVs Associated proteins or transcripts Exon length (aa) Type1 Type2
G29 chr.16:68567795-68568136 342 1 0 1 NR_003610, PDXC2 * (U) - 1 0
  chr.18:11928734-11929237 504 2 2 0 - - - -
  chr.16:14952973- 408 3 0 4 BC023572 * (M) - 2 0
  14953380      NP_008916, morpheus (B) 136 3 0
  chr.16:15365020-15365427 408 3 0 2 - - - -
  chr.16:11609511-11609918 408 3 1 0 - - - -
  chr.16:28261432-28262010 579 3 2 1 - - - -
  chr.16:15105678-15106116 439 4 0 1 - - - -
  chr.16:16351450-16351914 465 4 0 3 BAC85871 (U) 155 4 0
  chr.16:16394814-16395312 465 4 0 3 NP_848636 (M) 155 4 0
  chr.16:18319329-18319793 465 4 0 5 NP_848636 (M) 155 4 0
  chr.16:18359482-18359946 465 4 0 5 NP_848636 (M) 155 4 0
  chr.16:28375249-28375848 600 4 2 2 - - - -
  chr.16:28690975-28691574 600 4 2 4 - - - -
  chr.16:28576850-28577449 600 4 2 5 - - - -
  chr.16:72982790-72983476 687 4 2 5 AAI60029, NPIPL2 (U) 229 4 2
  chr.16:28970894-28971553 660 4 2 1 - - - -
G40 chr.16:22452448-22455204 2757 35 4 12 NP_001129337 (U) 919 35 4
       AAH94882 (B) 544 18 4
       NP_569731, NPIPL3 (B) 464 14 4
  chr.16:29300271-29303111 2841 37 3 2†‡ - - - -
  chr.16:30141785-30144625 2841 37 4 2 BAC87606 (B) 794 29 4
  chr.16:21321092-21324115 3024 39 4 5†§ BAG65049 (U) 970 39 3
       BAG64593 (U) 849 31 4
       NP_569731 (B) 464 14 4
  chr.16:21753543-21756566 3024 39 4 10 BAA13210 (B) 840 31 4
  1. The paralogous sequences of morpheus exon 8 were detected and characterized for the presence and number of type 1 and 2 ITRs. Group IDs refer to Additional file 1. Exon length is reported in base pairs and in amino acids (aa) only when supported by coding mRNAs. Unique (U), best (B) or multiple (M) transcript support is reported for each locus. CNVs that overlap the genomic locus of exon 8 are indicated. *ITRs residing in non-coding RNAs. CNVs overlapping exclusively with ITRs, and corresponding to identifiers 30774, §30757 and 30761 of the Database of Genomic Variants.