Expansion of the human mitochondrial proteome by intra- and inter-compartmental protein duplication

Table 1 Duplications in gene families with products localized to the mitochondria

Human localization of gene family	Yeast localization of gene family	Number of families	Number of human proteins
Mitochondrial	Mitochondrial	53	118
Mitochondrial and non-mitochondrial	Non-mitochondrial	26	101
Other	Other	25	55

'Mitochondrial' denotes mitochondrial localization for all genes from this family in a species; 'non-mitochondrial' indicates a known localization to another subcellular compartment; 'mitochondrial and non-mitochondrial' indicates families with both mitochondrial and non-mitochondrial paralogs. See also Table S4 in Additional data file 1 for other duplication classes.

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