Enrichment of sequencing targets from the human genome by solution hybridization

Table 2 Uniformity of sequence coverage

Sample	Replicate	Mean coverage	Proportion of mapped bases on targets¹ (%)
			>1 read	<1/5	1/5 to <5	>5
NA15510	Capture 1	30.8	98.24	10.27	89.71	0.02
NA15510	Capture 2	27.6	98.34	9.34	90.64	0.02
HE00069	Capture 1	29.0	98.24	8.98	91.00	0.02
HE00069	Capture 2	28.8	98.40	8.48	91.51	0.02
	Average	29.1	98.31	9.27	90.72	0.02

¹Percentage of all bases that had more than one read or had a sequence depth of less than 1/5 the mean coverage, between 1/5 and 5 times the mean, and greater than 5 times the mean.

ISSN: 1474-760X