Skip to main content
Figure 1 | Genome Biology

Figure 1

From: Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts

Figure 1

Increase in sequence coverage. (a) Mean sequence coverage by region. Transcript regions (5' UTR, CDS, 3' UTR) were divided into deciles, and the sequence coverage for each decile was averaged across all 887 target transcripts. Coverage is displayed for before hybrid selection (blue) and after hybrid selection (red). The average length of each region is 292, 2,136, and 1,729, respectively. (b) Distribution of sequence coverage for targeted genes. For each sequence-coverage threshold (x-axis), the fraction of 467 genes at or above that threshold is plotted (y-axis) for before hybrid selection (blue) and after hybrid selection (red).

Back to article page

Genome Biology

ISSN: 1474-760X

Contact us