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Table 1 REST-mediated changes in histone modifications in RE1 regions

From: Profiling RE1/REST-mediated histone modifications in the human genome

Factor

Promoter cRE1

Non-promoter cRE1

Promoter ncRE1

Non-promoter ncRE1

H2AK5ac

-

-

--

--

H2AK9ac

-

NC

-

-

H2BK120ac

--

-

--

--

H2BK12ac

--

-

--

--

H2BK20ac

--

-

--

--

H2BK5ac

--

-

--

-

H3K14ac

-

NC

-

NC

H3K18ac

--

-

--

--

H3K23ac

NC

NC

-

NC

H3K27ac

--

-

--

-

H3K36ac

--

-

--

--

H3K4ac *

--

-

--

--

H3K9ac

--

NC

--

NC

H4K12ac

-

--

-

--

H4K16ac

-

-

-

-

H4K5ac

--

-

--

--

H4K8ac

--

-

--

--

H4K91ac

--

-

--

--

H2BK5me1

+

-

+

-

H3K27me1

-

-

-

-

H3K27me2

+

+

+

+

H3K27me3

+

+

+

+

H3K36me1

NC

NC

NC

NC

H3K36me3

-

-

-

-

H3K4me1

--

-

-

--

H3K4me2

-

NC

-

-

H3K4me3

-

NC

-

NC

H3K79me1

-

-

--

--

H3K79me2

--

-

--

--

H3K79me3

--

-

--

--

H3K9me1

-

+

-

-

H3K9me2

+

+

+

+

H3K9me3

+

+

+

+

H3R2me1

NC

+

NC

NC

H3R2me2

NC

NC

NC

NC

H4K20me1

NC

NC

NC

-

H4K20me3

NC

NC

NC

NC

H4R3me2

+

NC

NC

NC

H2AZ

--

-

--

-

PolII

--

-

--

--

  1. RE1 regions with bound REST showed increased (plus signs) or decreased (minus signs) histone modifications when compared to RE1 sites without REST occupancy. Modifications without an apparent difference are indicated by 'NC' (for no change), and two minus signs (--) mark a larger magnitude of change than one minus sign (-).