Figure 1

RE1 and REST-mediated gene repression. The expression levels in CD4+ T-cells are shown as boxplots for all human genes (All genes), RE1 genes without REST (cRE1-REST and ncRE1-REST) and with REST (cRE1+REST and ncRE1+REST) in their promoters, and genes with RE1 motifs in the repetitive sequences of their promoters (RpRE1-REST and RpRE1+REST). Conversely, the genes with REST in their promoters are also separated into two groups, one with (REST+DJ-RE1) and the other without (REST-RE1) RE1s annotated in a previous study [19]. An asterisk indicates groups significantly (P < 0.001) different from all human genes with respect to their expression scores.