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Figure 7 | Genome Biology

Figure 7

From: Studying alternative splicing regulatory networks through partial correlation analysis

Figure 7

GG, EG, and EE links in the calcium signaling pathway. The gene layout is the same as the layout in the KEGG pathway database. A red line represents a GG link. The two gene pairs with GG links happen to also have EE links ('GG & EE'). A blue line represents an EE link and a green line represents an EG link. A dot at one end of a line is used to represent the exon in an EG link. The KEGG calcium signaling pathway is enriched with EG and EE links with p-values 0.01 and 0.001. However, GG links are not enriched in the pathway, with a p-value of 0.354. Each box represent the corresponding component in the KEGG database: 1, NCX; 2, PMCA; 3, GPCR; 4, SOC; 5, CaV1; 6, ROC; 7, GPCR; 8, PTK; 9, CD38; 10, Gs; 11, Gq; 12, ADCY; 13, PLCδ; 14, PLCβ; 15, PLCγ; 16, PLCε; 17, SPHK; 18, PKA; 19, PLN; 20, SERCA; 21, RYR; 22, IP3R; 23; CALM; 24, VDAC; 15, TnC; 26, MLCK; 27, PHK; 28, CaN; 19, CAMK; 30, NOS; 31, PDE1; 32, FAK2; 33, PKC; 34, PPID. A circle in a box represents a gene in the corresponding component.

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