Figure 6
From: Studying alternative splicing regulatory networks through partial correlation analysis
Enrichment of GG, EG, or EE links in functional gene sets. For each gene set with at least one GG, EG, or EE link, to test the significance of the enrichment of links, we simulated gene sets by randomly selecting the same number of genes as the tested gene set. The empirical p-value of the number of observed links was calculated as Pr (the number of links in the simulated gene set ≥ the number of observed links) from 1,000 simulations. Histograms of the p-values are plotted for those gene sets. The total number of test gene sets is listed on the histograms. C1: gene sets sharing a chromosomal cytogenetic band. C2: gene sets curated from pathway databases. C3: gene sets sharing a conserved cis-regulatory motif. C4: gene sets sharing a GO term.