Table 2 Pairwise HKA tests
From: The signature of long-standing balancing selection at the human defensin β-1 promoter
Intraspecific polymorphisms | Interspecific divergence | |||||
|---|---|---|---|---|---|---|
Gene | Sample size | Segregating sites | Silent sites | Differences | Sites | HKA p-value |
DEFB1 | 94 | 22 | 1,400 | 79 | 1,313 | - |
ADAM19 | 94 | 12 | 2,000 | 99 | 1,904 | 0.11 |
CCL2 | 94 | 7 | 2,000 | 114 | 1,989 | 0.010 |
LMAN1 | 94 | 8 | 2,000 | 107 | 1,887 | 0.018 |
LY86 | 94 | 17 | 2,000 | 133 | 1,964 | 0.13 |
PTGDR | 94 | 15 | 2,000 | 108 | 1,981 | 0.20 |
TGFA | 94 | 8 | 2,000 | 83 | 1,974 | 0.074 |
TNFRSF18 | 94 | 14 | 2,000 | 184 | 1,602 | 0.0014 |
CCL11 | 94 | 13 | 2,000 | 137 | 1,967 | 0.038 |
CCL5 | 94 | 7 | 2,000 | 104 | 1,726 | 0.0077 |
EGF | 94 | 10 | 2,000 | 96 | 1,851 | 0.061 |
EGFR | 94 | 11 | 2,000 | 117 | 1,986 | 0.047 |
IL17E | 94 | 10 | 2,000 | 101 | 1,978 | 0.066 |
IL17F | 94 | 14 | 2,000 | 87 | 1,962 | 0.32 |
IRAK3 | 94 | 5 | 2,000 | 152 | 1,952 | 0.00032 |
IL18R1 | 94 | 12 | 2,000 | 103 | 1,901 | 0.095 |
IL23A | 94 | 3 | 2,000 | 81 | 1,727 | 0.0030 |
MEFV | 94 | 7 | 2,000 | 116 | 1,941 | 0.0081 |
TGFB2 | 94 | 7 | 2,000 | 75 | 1,960 | 0.073 |
TGFBR1 | 94 | 1 | 2,000 | 83 | 1,991 | 0.0011 |
TLR4 | 94 | 6 | 2,000 | 140 | 1,985 | 0.0014 |