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Figure 6 | Genome Biology

Figure 6

From: Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions

Figure 6

Condition-specific essential gene identification by the three yeast models. The models are assessed here solely on their ability to identify genes that are essential under a given condition and not essential under YPD. The size of the pies is proportional to the number of genes essential under a given condition relative to other conditions. The largest number of condition-specific essential genes was the 43 found under YPAC, and hence the essential genes for this condition are represented by the largest pies. The number of essential genes identified under each condition with FBA is shown for the iFF708 (red), iLL672 (blue) and iND750 (green) models. Additional essential genes identified using MOMA are shown in a lighter shade and essential genes not identified are represented by the white slices. In all models, under virtually all conditions, the majority of condition specific essential genes are identified, indicating that the predictive abilities of the models are robust to different media conditions.

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