Conserved chromosomal clustering of genes governed by chromatin regulators in Drosophila

Table 6 Conservation of genes in the clusters and their vicinity

Genome	No. of clusters	No. of clusters conserved in D. melanogaster	No. of genes within the clusters	% Genes conserved within the clusters	% Genes conserved in the flanking area	% Genes conserved in artificial clusters	Divergence time estimates (Mya)
D. simulans	20	20 (100%)	144	96%	86%	90%	2-3
D. yakuba	25	21 (84%)	146	88%	64%	79%	5-7
D. pseudoobscura	14	12 (86%)	83	96%	58%	65%	25-55
A. gambiae	7	6 (86%)	48	66%	2%	20%	250-300

The following information is shown for each genome: the species, the number of clusters predicted, the number and the percentage of clusters that are conserved in D. melanogaster, the number of genes in the clusters (the same amount of genes is used to measure the conservation in the flanking areas), the percentage of genes that are conserved between these clusters and the corresponding clusters in D. melanogaster, the percentage of genes that are conserved in the flanking areas of the clusters (average conservation in the left and right flanking areas), the percentage of the genes that are conserved in 10,000 artificial clusters sampled on each species, and the divergence time (million years ago (Mya)) estimates between D. melanogaster and each species, extracted from [58, 101].

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