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Table 3 Partial correlations in expression levels for the different mice of this study

From: Gene expression regulation in the context of mouse interspecific mosaic genomes

 

Correlation coefficients between expression levels, corrected for reciprocal parental effect

 

All transcripts (37,431)

All transcripts in the 11 segments (2,319)

Modifed transcripts in the M. spretus segments (143)

 

Correlation coefficient

p-value

Correlation coefficient

p-value

Correlation coefficient

p-value

B6 versus IRCSs

0.9561

<0.0001

0.8189

<0.0001

-0.1499

NS

SEG versus IRCSs

0.0155

NS

0.3639

<0.0001

0.5441

<0.0001

  1. Partial correlations for the fluorescence levels of the various transcripts between the two parental species and the IRCSs taken as a whole. Three classes are considered, either with all the genes detectable on the array, or only the genes present inside the M. spretus segments, or only genes modified at the 4X threshold inside these segments. While even inside the M. spretus segments, most genes are not dysregulated, a class of genes that are strictly driven by the M. spretus context appears, since the correlation between the IRCSs and SEG does not significantly decrease when the B6 parental effect is removed (from 0.5963 to 0.5441; see Table 2). NS, not significant.