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Table 1 Dysregulated genes (compared to B6 expression levels) in M. spretus and the IRCSs

From: Gene expression regulation in the context of mouse interspecific mosaic genomes

All genes considered

    

   Pan genomic (37,432)

SEG

44H

137F

97C

   Under-expressed

3,290

57

15

26

   Over-expressed

3,560

19

45

2

   ∑

6,850

76

60

28

   Percentage of modified genes

20.90

0.23

0.18

0.09

   Proportion of under-expressed (%)

48.0

75.0

25.0

92.9

Only genes inside B6 segments considered

    

   Genetic background (variable number according to the strain)

 

44H

137F

97C

   Under-expressed

 

21

2

11

   Over-expressed

 

3

30

0

   ∑

 

24

32

11

   Percentage of modified genes

 

0.06

0.09

0.03

   Proportion of under-expressed (%)

 

87.5

6.3

100.0

  1. A statistical overview of genes with modified expression in the various genomic contexts examined in this study, compared to the B6 strain taken as a reference.