Figure 11

The proportion of testis-specific genes in the different subgenomes studied. Significantly different values are represented by horizontal brackets (at least significant at p < 0.01). On average, the segments are enriched in testis-specific genes, essentially owing to the bulk of genes from class 0 (75%). By contrast, class 1 is depleted in testis-specific genes, suggesting that trans-driven dysregulation (forcing M. spretus genes to a B6 behavior) is strongly counter-selected. The increased number of testis-specific genes in the segments could be due to a positive selection aiming at compensating deleterious effects on reproductive parameters during the process of strain establishment. **p-value < 0.01; ***p-value < 0.001.