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Table 4 Expression of genes encoding secreted molecules with potential suppressive function

From: The IL-10 and IFN-γ pathways are essential to the potent immunosuppressive activity of cultured CD8+NKT-like cells

Symbol Function NKT/nCD8 CD4/nCD8 aCD8/nCD8 NKT/nCD8 (q) CD4/nCD8 (q) aCD8/nCD8 (q)
Spp1 Suppression 251.4 203.8 7.4 9.9E-06 2.6E-06 1.2E-02
Lgals3 (Gal3) Suppression 87.0 38.5 3.1 2.6E-07 1.7E-04 4.9E-02
Esm1 Suppression 74.5 2.8 1.2 4.2E-04 2.2E-02 5.8E-01
Fgl2 Suppression 32.7 0.9 0.9 9.2E-05 3.0E-01 6.3E-01
Tnfrsf11b (Opg) Suppression 29.0 1.1 1.1 2.4E-04 3.0E-01 7.0E-01
Lgals1 (Gal1) Suppression 27.1 22.3 6.0 1.4E-04 7.8E-04 6.1E-02
Gzmd Killing 834.8 25.8 1.1 2.1E-07 1.0E-02 6.6E-01
Gzme Killing 524.9 27.3 0.9 2.3E-06 6.8E-03 6.4E-01
Gzmc Killing 446.4 25.7 2.1 2.7E-07 3.3E-02 1.8E-01
Gzmg Killing 328.8 5.5 1.0 1.2E-05 1.8E-02 8.0E-01
Gzmb Killing 104.6 60.2 85.6 2.2E-06 2.4E-04 2.8E-03
Gzmf Killing 63.5 1.8 1.3 6.9E-04 9.4E-03 4.1E-01
Gzma Killing 61.5 17.1 0.4 1.2E-05 6.8E-03 1.2E-01
Prf1 Killing 29.0 1.0 1.7 4.4E-04 4.1E-01 2.8E-01
Gzmk Killing 23.3 0.5 0.6 1.5E-04 1.7E-02 2.7E-01
Ifng Cytokine 51.2 50.3 258.7 3.3E-03 1.5E-02 8.2E-04
Il10 Cytokine 47.2 122.8 2.1 1.8E-03 1.6E-05 4.0E-02
Il24 Cytokine 5.5 33.0 1.0 5.1E-02 3.5E-04 8.1E-01
Lta Cytokine 3.9 5.1 27.8 3.1E-03 2.2E-04 2.7E-03
Ccl3 Chemokine 86.2 162.4 177.9 3.4E-04 1.2E-03 1.3E-03
Ccl4 Chemokine 25.5 20.8 18.7 6.6E-04 3.5E-03 4.1E-03
Ccl9 Chemokine 11.3 53.7 4.4 1.5E-02 5.2E-04 4.5E-02
Cklfsf7 Chemokine 4.7 1.2 0.9 3.4E-03 1.8E-01 7.1E-01
  1. NKT, CD8+ NKT-like cells; nCD8, naïve CD8+ T cells; cCD4, cultured CD4+ T cells; aCD8, activated CD8+ T cells.