Table 3 Transcription factors differentially expressed in CD8+ NKT-like cells
Symbol | Function | NKT/nCD8 | CD4/nCD8 | aCD8/nCD8 | NKT/nCD8 (q) | CD4/nCD8 (q) | aCD8/nCD8 (q) |
|---|---|---|---|---|---|---|---|
Nfil3 | NF | 19.7 | 22.3 | 4.3 | 4.0E-04 | 3.6E-04 | 3.4E-02 |
Mycn (Nmyc1) | TF | 20.8 | 2.2 | 1.1 | 8.0E-05 | 2.7E-02 | 6.8E-01 |
Irf8 (Icsbp1) | TF | 14.4 | 1.9 | 19.2 | 1.7E-04 | 3.2E-02 | 3.7E-03 |
Irf4 | TF | 4.7 | 24.7 | 18.2 | 1.6E-03 | 4.7E-05 | 6.2E-03 |
Litaf | TF | 10.3 | 5.0 | 4.8 | 4.5E-05 | 1.4E-04 | 1.6E-02 |
Runx2 | TF | 8.6 | 3.5 | 1.8 | 2.2E-04 | 5.2E-02 | 3.4E-01 |
Pbx3 | TF | 5.8 | 6.2 | 1.6 | 4.1E-04 | 4.8E-04 | 3.6E-01 |
Jun (AP1) | TF | 5.8 | 2.9 | 2.6 | 8.9E-04 | 8.8E-02 | 1.2E-01 |
Cgrrf1 | TF | 4.9 | 4.9 | 2.8 | 2.2E-04 | 2.7E-03 | 7.7E-02 |
Eomes | TF | 4.0 | 0.2 | 0.6 | 9.7E-04 | 3.8E-04 | 4.5E-01 |
Atf4 | TF | 3.8 | 2.0 | 3.1 | 6.4E-03 | 3.1E-03 | 2.0E-02 |
Zbtb32 (Rog) | TF (ZF) | 9.3 | 1.8 | 3.9 | 1.2E-03 | 3.9E-02 | 1.6E-02 |
Zdhhc2 | TF (ZF) | 4.9 | 2.6 | 1.5 | 9.3E-04 | 1.5E-03 | 4.6E-01 |
Zfp313 | TF (ZF) | 4.3 | 2.2 | 1.2 | 1.9E-02 | 6.6E-03 | 6.8E-01 |
Zfp608 | TF (ZF) | 3.9 | 1.2 | 1.7 | 4.2E-04 | 1.1E-01 | 1.3E-01 |
Rnf128 | TF (RF) | 6.2 | 10.4 | 1.0 | 5.8E-04 | 7.8E-04 | 8.0E-01 |
Rnf13 | TF (RF) | 4.0 | 1.7 | 1.2 | 8.5E-04 | 7.3E-02 | 7.0E-01 |
Socs2 | Suppressor | 48.6 | 104.0 | 27.8 | 3.5E-05 | 3.3E-05 | 3.9E-03 |
Cish (Socs) | Suppressor | 8.8 | 9.5 | 4.9 | 1.2E-04 | 5.2E-05 | 1.3E-02 |
Tcf7 | TF | 0.012 | 0.061 | 0.274 | 5.7E-07 | 1.4E-03 | 7.7E-02 |
Klf3 | TF (KR) | 0.012 | 0.014 | 0.034 | 9.4E-08 | 5.9E-06 | 8.1E-03 |
Klf2 | TF (KR) | 0.04 | 0.03 | 0.01 | 4.3E-04 | 5.5E-04 | 2.7E-03 |
Klf1 | TF (KR) | 0.05 | 0.05 | 0.06 | 3.5E-05 | 1.7E-04 | 1.0E-02 |
Rkhd3 | TF (RF) | 0.15 | 0.17 | 0.16 | 1.1E-04 | 1.7E-04 | 9.1E-03 |
Bcl11a | TF (ZF) | 0.15 | 0.16 | 0.15 | 2.4E-04 | 1.1E-03 | 2.3E-02 |
Zbtb20 | TF (ZF) | 0.20 | 0.15 | 0.16 | 1.2E-04 | 3.2E-04 | 6.3E-03 |