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Table 2 Major biological processes modified in the cultured CD8+ NKT-like cells

From: The IL-10 and IFN-γ pathways are essential to the potent immunosuppressive activity of cultured CD8+NKT-like cells

  ≥5 fold (314) ≥10 fold (113)
Biological process Number of genes % genes p-value OR Number of genes % genes p-value OR
Immunity and defense 56 17.80% 2.0E-11 3.1 35 31.00% 7.7E-15 6.3
Apoptosis 25 8.00% 8.8E-10 4.8 19 16.80% 2.2E-13 11.3
Lipid, fatty acid metabolism 25 8.00% 7.5E-06 2.9 6 5.30% 0.1161 1.9
Signal transduction 74 23.60% 3.4E-05 1.8 28 24.80% 0.0041 1.9
Cell structure and motility 25 8.00% 0.0004 2.2 11 9.70% 0.0036 2.8
Cell cycle 23 7.30% 0.0004 2.3 11 9.70% 0.0015 3.1
Oncogenesis 14 4.50% 0.0005 3.0 8 7.10% 0.0004 4.9
Protein metabolism and modification 60 19.10% 0.0009 1.6 23 20.40% 0.0152 1.8
Cell proliferation and differentiation 21 6.70% 0.0023 2.1 13 11.50% 0.0001 3.8
Carbohydrate metabolism 14 4.50% 0.0053 2.3 2 1.80% 0.6720 0.9
Sulfur metabolism 5 1.60% 0.0059 4.6 0    
Other metabolism 13 4.10% 0.0159 2.0 6 5.30% 0.0319 2.6
Cell adhesion 12 3.80% 0.0528 1.7 6 5.30% 0.0424 2.5
Others 176 56.10%    53 24.80%   
  1. OR, odds ratio.