Table 2 Major biological processes modified in the cultured CD8+ NKT-like cells
≥5 fold (314) | ≥10 fold (113) | |||||||
|---|---|---|---|---|---|---|---|---|
Biological process | Number of genes | % genes | p-value | OR | Number of genes | % genes | p-value | OR |
Immunity and defense | 56 | 17.80% | 2.0E-11 | 3.1 | 35 | 31.00% | 7.7E-15 | 6.3 |
Apoptosis | 25 | 8.00% | 8.8E-10 | 4.8 | 19 | 16.80% | 2.2E-13 | 11.3 |
Lipid, fatty acid metabolism | 25 | 8.00% | 7.5E-06 | 2.9 | 6 | 5.30% | 0.1161 | 1.9 |
Signal transduction | 74 | 23.60% | 3.4E-05 | 1.8 | 28 | 24.80% | 0.0041 | 1.9 |
Cell structure and motility | 25 | 8.00% | 0.0004 | 2.2 | 11 | 9.70% | 0.0036 | 2.8 |
Cell cycle | 23 | 7.30% | 0.0004 | 2.3 | 11 | 9.70% | 0.0015 | 3.1 |
Oncogenesis | 14 | 4.50% | 0.0005 | 3.0 | 8 | 7.10% | 0.0004 | 4.9 |
Protein metabolism and modification | 60 | 19.10% | 0.0009 | 1.6 | 23 | 20.40% | 0.0152 | 1.8 |
Cell proliferation and differentiation | 21 | 6.70% | 0.0023 | 2.1 | 13 | 11.50% | 0.0001 | 3.8 |
Carbohydrate metabolism | 14 | 4.50% | 0.0053 | 2.3 | 2 | 1.80% | 0.6720 | 0.9 |
Sulfur metabolism | 5 | 1.60% | 0.0059 | 4.6 | 0 | |||
Other metabolism | 13 | 4.10% | 0.0159 | 2.0 | 6 | 5.30% | 0.0319 | 2.6 |
Cell adhesion | 12 | 3.80% | 0.0528 | 1.7 | 6 | 5.30% | 0.0424 | 2.5 |
Others | 176 | 56.10% | 53 | 24.80% | ||||