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Figure 3 | Genome Biology

Figure 3

From: The transcriptional program underlying the physiology of clostridial sporulation

Figure 3

Investigation of the sporulation cascade in C. acetobutylicum. (a-f) Expression profiles of sporulation genes shown as ratios against the first expressed timepoint. (a) The first three sporulation factors: spo0A (red filled triangles), sigH (black filled squares), and sigF (open blue circles). (b) spo0A (red filled triangles) and possible sporulation regulators: abrB (open black circles) and sinR (green filled diamonds). (c) Sporulation factors downstream of spo0A: sigF (open blue circles), sigE (black filled triangles), and sigG (open red squares). (d) Genes related to sigK expression: spoIIID (blue filled diamonds), yabG (red filled triangles), and spsF (black filled triangles). (e) spoIIA operon: spoIIAA (black filled diamonds), spoIIAB (red filled triangles), and sigF (open blue circles). (f) spoIIG operon and sigG: spoIIGA (green filled diamonds), sigE (black filled triangles), and sigG (open red squares). The gray bar indicates the onset of transitional phase. (g) Ranked expression intensities. White denotes a rank of 1, while dark blue denotes a rank of 100 (see scale). Gray squares indicate timepoints at which the intensity did not exceed the threshold value. Bracketed genes are predicted to be coexpressed as an operon.

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