From: Identification of transcripts with enriched expression in the developing and adult pancreas
Cluster | Number of tags in the cluster | Number of genes in the cluster | Number of genome maps in the cluster | Number assessed by GenePaint* | Number assessed by QPCR | Median S†| Previously characterized genes in the cluster | Selected GO categories and KEGG pathways enriched in the cluster‡ |
---|---|---|---|---|---|---|---|---|
1 | 154 | 85 | 61 | 37 | 3 | 0.0079 | Nkx6-2 | Transcriptional activator activity p = 0.02; development p = 0.049 |
2 | 49 | 29 | 19 | 15 | 2 | 0.0037 | Â | Metabolism p = 0.01; cell organization and biogenesis p = 0.035 |
3 | 58 | 40 | 15 | 14 | 2 | 0.0044 | Â | Receptor activity p = 0.028; development p = 0.030 |
4 | 292 | 115 | 175 | 45 | 4 | 0.00895 | Hes6, Pdx1, Sox9 | Regulation of transcription p = 0.027; maturity onset diabetes of the young p = 0.002 |
5 | 1,008 | 427 | 542 | 175 | 13 | 0.03555 | Arx, Gcg, Ghrl, Iapp, Isl1, Nkx2-2, Myt1, Neurog3, Neurod1, Pax4, Pax6, Pou3f4, Pyy | Secretory pathway p < 0.001; hormone activity p = 0.049; maturity onset diabetes of the young p < 0.001 |
6 | 60 | 41 | 17 | 16 | 1 | 0.00465 | Â | Â |
7 | 21 | 11 | 10 | 7 | 1 | 0.008 | Â | Â |
8 | 78 | 46 | 28 | 29 | 5 | 0.012 | Pax6 | Eye morphogenesis p = 0.020; type II diabetes mellitus p = 0.001 |
9 | 23 | 16 | 6 | 10 | 2 | 0.0041 | Â | Cell proliferation p = 0.028 |
10 | 401 | 281 | 107 | 122 | 4 | 0.0158 | Id2 | Response to endogenous stimulus p = 0.021 |
11 | 76 | 57 | 10 | 23 | 1 | 0.00555 | Amy1, Cel, Clps, Ela1, Pnliprp2, Reg1 | Protein catabolism p = 0.002 |
12 | 154 | 122 | 13 | 56 | 3 | 0.0074 | Ela1, Pnlip, Reg3d | Growth factor binding p = 0.005; carboxypeptidase activity p = 0.013; regulation of cell growth p = 0.027 |
13 | 136 | 84 | 42 | 30 | 3 | 0.01835 | Iapp, Ins1, Ins2 | Secretion p = 0.03; maturity onset diabetes of the young p < 0.001; type II diabetes mellitus p < 0.001; type I diabetes mellitus p = 0.003 |
14 | 56 | 47 | 4 | 22 | 0 | 0.00335 | Â | Protein metabolism p = 0.020 |