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Figure 6 | Genome Biology

Figure 6

From: Identification of motifs that function in the splicing of non-canonical introns

Figure 6

G-rich and C-rich motifs function combinatorially in LCAT intron 4 splicing. (a) LCAT intron 4 with the mutations shown in blue above the WT sequence. BPS, branchpoint. (b) Splicing of the LCAT intron 4 mini-genes (WT, MUT1, MUT3, MUT6, MUT 24 and MUT 25) in HeLa cells. Analysis was performed as in Figure 4. (c) Graphical representation of the percent pre-mRNA for each LCAT mini-gene. Error bars represent standard deviation of replicate experiments.

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