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Table 1 A selection of identified relevant clusters in the set of differentially expressed genes between metastatic and localized prostate cancer

From: Anni 2.0: a multipurpose text-mining tool for the life sciences

Cluster

Number of genes

Descriptive concepts

Up-regulated

  

   A

24

Kinetochores; mitosis; anaphase-promoting complex

   B

5

Nuclear proteins; tumor markers, biological

   C

3

Unfolded protein response

Down-regulated

  

   A

7

Complement system proteins

   B

7

Calponin; smooth muscle myosins

   C

4

Myosin phosphatase; smooth muscle (tissue)

   D

7

Extracellular matrix proteins

   E

5

Transcription factor; proto-oncogene proteins c-fos

   F

4

Cyclin-dependent kinases

   G

3

Melanosomes; membrane protein traffic; exocytosis

   H

5

Membrane transport proteins; symporter

  1. The most descriptive concepts are shown as given by the Anni annotation view. The two left-most columns depict how many genes in the cluster were either up- or down-regulated in metastasized prostate cancer.