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Table 3 Mouse SuperArray data showing greater than twofold cell stress RNA expression changes in the cerebellum of Wldsmice compared with wild-type controls

From: Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds)

Gene name Symbol Acc. number Array cell Fold change SD Cell stress and toxicity function
Serine (or cysteine) peptidase inhibitor, clade E, member 1 Serpine1 NM_008871 G01 3.73 0.29 Inflammation
Interleukin 1 beta Il1b NM_008361 E11 3.69 0.82 Inflammation
Transformed mouse 3T3 cell double minute 2 Mdm2 NM_010786 F02 3.34 0.15 Growth arrest and senescence
Cytochrome P450, family 2, subfamily a, polypeptide 5 Cyp2a5 NM_007812 B08 2.92 0.48 Oxidative or metabolic stress
Fas ligand (TNF superfamily, member 6) Fasl NM_010177 C11 2.62 0.71 Apoptosis signaling
Bcl2-like 1 Bcl2l1 NM_009743 A04 -2.11 0.25 Apoptosis signaling
Cyclin C Ccnc NM_016746 A10 -2.44 0.46 Proliferation and carcinogenesis
Chemokine (C-C motif) ligand 21b Ccl21b NM_011124 A07 -3.37 0.25 Inflammation
Chemokine (C-C motif) ligand 4 Ccl4 NM_013652 A09 -3.86 0.40 Inflammation
Annexin A5 Anxa5 NM_009673 A01 -4.00 1.50 Apoptosis signaling
Ataxia telangiectasia mutated homolog (human) Atm NM_007499 A02 -4.99 0.70 DNA damage and repair
Caspase 1 Casp1 NM_009807 A05 -6.81 7.58 Apoptosis signaling
Cytochrome P450, family 3, subfamily a, polypeptide 11 Cyp3a11 NM_007818 B12 -8.60 0.52 Oxidative or metabolic stress
Chemokine (C-C motif) ligand 3 Ccl3 NM_011337 A08 -9.50 2.39 Inflammation
  1. eGFP, enhanced green fluorescent protein; SD, standard deviation.