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Table 2 Summary of histopathological diagnoses and severities

From: Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype

  Severity
Histopathological diagnosis None Minimal Mild Moderate Marked
Centrilobular hepatocyte necrosis 304 65 15 8 26
Centrilobular, mid-zonal hepatocyte necrosis 399 8 5 4 2
Mid-zonal hepatocyte necrosis 417 1 0 0 0
Focal hepatocyte necrosis 392 11 12 2 1
Centrilobular cellular infiltrates 333 50 17 13 5
Centrilobular, mid-zonal cellular infiltrates 400 5 8 5 0
Portal cellular infiltrates 394 16 5 3 0
Focal cellular infiltrates 370 34 10 4 0
Depletion glycogen 324 19 33 16 26
Centrilobular hepatocyte degeneration 403 9 3 3 0
Centrilobular, mid-zonal hepatocyte degeneration 402 4 7 5 0
Hepatocyte apoptosis 410 7 1 0 0
Hepatocyte hypertrophy 382 10 16 0 10
Hepatocyte fatty change 416 2 0 0 0
Bile duct hyperplasia 405 11 2 0 0
Congestion 397 10 5 6 0
Hemorrhage 384 34 0 0 0
Hepatocyte regeneration 412 3 0 2 1
Mitosis 393 12 5 4 4