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Figure 7 | Genome Biology

Figure 7

From: Dynamic instability of the major urinary protein gene family revealed by genomic and phenotypic comparisons between C57 and 129 strain mice

Figure 7

Summary of Mup cluster transcriptional and phenotypic profiles. The cluster of B6 is presented as annotated in Figure 1. Red arrows and red text boxes indicate tissues in which transcription can be confirmed for each locus based on the presence of 100% supporting cDNAs or ESTs in GenBank [42] (whilst allowing for poor-quality sequence at the immediate 5' and 3' ends for ESTs); blue arrows and blue text boxes indicate genes where a corresponding protein has been detected in urine. The asterisks marking genes 5, 10 and 13 indicate that potentially corresponding proteins for these loci have previously been detected in wild mice, but not in the inbred mice studied in this investigation [46] (see Results). Genes 4, 6, 7, 9, 12, 14 and 15 each have proteins with predicted masses that can be matched to detected mass 18,693 Da; it is currently unclear which of these loci contribute to the protein peak in Figure 4. Proteins that exhibit sexual dimorphism (being detected in males but not females) are indicated by green arrows and text boxes marked 'Male'.

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