The Knowlet-based connections of four yeast proteins. (a) The composite Knowlet of the four yeast proteins as indicated in the text. (b) When the (factually connected) concept 'mitosis' is selected for explanation in the Knowlet, the factual association appears to be based on GO annotations. (c) Multiple co-occurrences are also found with more than one source concept including S. cerevisiae and CDC28. (d) In addition, there are multiple concepts that indirectly connect the source concepts with cell division. This means that the original example sentence used for this case study would have been repeatedly retrieved as relevant in the 'explain' window, supporting by co-occurrence the semantic association between the proteins involved.