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Table 2 Summary of patient population and invasive characteristics of corresponding stem cell cultures in vitro

From: Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions

Patient number Age (years) Origin Gleason score % Invasion in vitro*
228 - LN metastasis 7 101 ± 21
434 59 Prostate 8/9 99 ± 56
484 69 Prostate 7 105 ± 29
512 74 Prostate BPH -
561 72 Prostate BPH -
563 64 Prostate 7 35 ± 9.5
569 64 Prostate 8 75 ± 9
574 74 Prostate BPH/G6 (5%) -
605 56 LN metastasis 7 119 ± 21
661 78 Prostate 6 -
627 79 Prostate BPH -
662 66 Prostate BPH -
665 53 Prostate 7 63 ± 18.4
667 47 Prostate 6 61 ± 4.2
687 63 Prostate 7 74
690 79 Prostate BPH -
693 75 Prostate BPH -
704 64 Prostate 7 (HR) -
003/06 52 Prostate 6 -
  1. *Invasion assays were carried out on total epithelial cell populations before fractionation according to [4]. Positive controls for invasive capacity were cell lines MCF7 and PC3M whose invasion score was 18-36%, whereas normal cell lines PNT2 and PNT1a and BPH/primary normal prostate invasion scores ranged from 3-6%. Patient 704 was being treated (hormone refractory (HR)) by androgen blockade therapy.