Overlap between three methods of detecting miRNA signatures on mRNA expression profiles. Results from eight tissues are presented in separate Venn diagrams. Each circle in the Venn diagrams indicates the number of miRNAs with significantly low target gene expression as predicted by the t-test, Wilcoxon or RR methods. For all tissues there was significant overlap amongst predicted miRNAs, with the Wilcoxon rank sum test and absolute expression t-test in strongest agreement. The numbers of miRNAs predicted by all three methods are indicated in bold.