Figure 4
From: Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly
Quantification of gene expression change by qPCR. Comparison of gene expression between normal skin (NS) and wounds (W) from young (pink) and old (blue) human subjects. (a) All estrogen-regulated genes tested displayed clear differential wound expression (red double-ended arrow) with more parity of expression in normal skin. (b) In contrast, genes identified as age-associated displayed pronounced changes in normal skin (blue double-ended arrow) of similar or greater magnitude than the wound gene expression change. n = 3-5 per group.