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Table 2 MICs of a variety of antimicrobials against S. maltophilia K279a and derivatives lacking specific functional RND efflux pump genes

From: The complete genome, comparative and functional analysis of Stenotrophomonas maltophiliareveals an organism heavily shielded by drug resistance determinants

 

Gent

Kan

Ami

Tob

Ery

Chor

Mero

Imi

Azt

Ctz

Pip

Tet

Min

Trim

Sul

Cipro

Levo

Nor

K279a

16

256

64

32

>1,024

6

32

256

256

8

64

16

0.25

32

64

2

4

32

smeJ

8

256

32

32

>1,024

6

32

256

512

8

64

8

0.125

32

64

1

4

32

smeK

8

256

32

32

>1,024

6

32

256

512

8

64

8

0.125

32

64

1

4

32

smeJK

8

256

32

32

>1,024

6

32

256

512

8

64

8

0.125

32

64

1

4

32

smeZ

1

128

32

16

>1,024

6

32

256

512

8

64

16

0.25

32

64

2

4

32

  1. Gent, gentamicin, Kan, kanamycin; Ami, amikacin; Tob, tobramycin; Ery, erythromycin; Chor, chloramphenicol; Mero, meropenem; Imi, imipenem; Azt, aztreonam; Ctz, ceftazidime; Pip, piperacillin; Tet, tetracycline; Min, minocycline; Trim, trimpethoprim; Sul, sulphamethoxazole; Cipro, ciprofloxacin; Levo, levofloxacin; Nor, norfloxacin.
  2. Entries in bold indicate changes of the MIC in the mutants compared to wild type K279a. The units used are in mg/L