Gene and metabolite levels in the central metabolic routes and the diversion of key intermediates to biosynthetic pathways. Genes are represented in green text, and metabolites in orange text. Ancestor and evolved strain-specific gene expression comparisons are denoted in green boxes (M, MG1655; D, DH10B). Ancestor and evolved strain-specific metabolite abundance comparisons are denoted in orange boxes (m, MG1655; d, DH10B). Logarithmically transformed (to base 2) response ratios were utilized for each comparison according to the log2 ratio scale on the upper right inset.