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Table 1 GO biological process categories with the highest and lowest SNP A/S ratios

From: Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective

GO accession

A/S ratio

Number of proteins

GO description

GO:0007608

0.72

298

Sensory perception of smell

GO:0050896

0.54

403

Response to stimulus

GO:0007565

0.48

43

Female pregnancy

GO:0006298

0.47

29

Mismatch repair

GO:0031424

0.46

22

Keratinization

GO:0007186

0.43

600

G-protein coupled receptor protein signaling pathway

GO:0007131

0.42

20

Meiotic recombination

GO:0008033

0.40

26

tRNA processing

GO:0045087

0.39

57

Innate immune response

GO:0006633

0.37

20

Fatty acid biosynthetic process

GO:0006986

0.14

40

Response to unfolded protein

GO:0006445

0.14

26

Regulation of translation

GO:0006096

0.14

37

Glycolysis

GO:0007420

0.13

25

Brain development

GO:0006334

0.13

38

Nucleosome assembly

GO:0006816

0.12

61

Calcium ion transport

GO:0007411

0.12

20

Axon guidance

GO:0006333

0.10

22

Chromatin assembly or disassembly

GO:0000398

0.09

62

Nuclear mRNA splicing, via spliceosome

GO:0007205

0.07

21

Protein kinase C activation

  1. Top part: ten GO categories with the highest A/S ratios. Bottom part: ten GO categories with the lowest A/S ratios.