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Table 2 Summary of GO analysis for D- and S-pair duplicates

From: Functional diversification of duplicate genes through subcellular adaptation of encoded proteins

 

D-pair

S-pair

  

Biological process*

No.

Percentage

No.

Percentage

P-value†

Excess‡

Biosynthetic process

32

21.1

111

42.9

0.0008

56

Catabolic process

32

21.1

17

6.6

0.0024

22

Regulation of biological process

59

38.8

56

21.6

0.0172

26

Response to biotic stimulus

0

0.0

12

4.6

0.1480

12

Nitrogen compound metabolic process

4

2.6

21

8.1

0.3988

14

Cell communication

18

11.8

15

5.8

0.4587

9

Primary metabolic process

110

72.4

210

81.1

0.5012

23

Cell cycle

21

13.8

20

7.7

0.5012

9

Response to endogenous stimulus

12

7.9

9

3.5

0.5012

7

Chemical homeostasis

0

0.0

6

2.3

0.5012

6

Cellular developmental process

11

7.2

9

3.5

0.5012

6

Chromosome segregation

5

3.3

2

0.8

0.5012

4

Cell division

21

13.8

25

9.7

0.6028

6

Response to stress

24

15.8

29

11.2

0.6483

7

Reproductive process

14

9.2

15

5.8

0.6696

5

Conjugation

7

4.6

6

2.3

0.6982

3

Sexual reproduction

7

4.6

6

2.3

0.6982

3

Aging

1

0.7

6

2.3

0.7084

4

Cellular metabolic process

120

79.0

214

82.6

0.7686

9

Asexual reproduction

3

2.0

2

0.8

0.7686

2

Nuclear division

1

0.7

0

0.0

0.7686

1

Protein localization

10

6.6

23

8.9

0.7785

6

Cell adhesion

0

0.0

2

0.8

0.7785

2

Response to chemical stimulus

17

11.2

25

9.7

0.8583

2

RNA localization

6

4.0

9

3.5

0.9959

1

Anatomical structure development

12

7.9

19

7.3

1

1

Establishment of localization

33

21.7

55

21.2

1

1

Macromolecule metabolic process

98

64.5

169

65.3

1

2

Response to external stimulus

0

0.0

1

0.4

1

1

Maintenance of localization

1

0.7

1

0.4

1

0

Response to abiotic stimulus

4

2.6

7

2.7

1

0

Cell organization and biogenesis

57

37.5

97

37.5

1

0

Regulation of biological quality

8

5.3

14

5.4

1

0

Autophagy

0

0.0

1

0.4

1

1

Filamentous growth

8

5.3

13

5.0

1

0

Cell homeostasis

7

4.6

12

4.6

1

0

Regulation of a molecular function

1

0.7

3

1.2

1

1

Cell proliferation

0

0.0

1

0.4

1

1

Non-developmental growth

1

0.7

2

0.8

1

0

  1. *We selected GO level 3, since this constitutes a good compromise between the number of genes annotated and the depth of the information contained in each class [46]. †After false discovery rate correction. ‡Represents the difference between the observed number of genes in the over-represented set and what would be expecated based on the observed genes in the other gene set.