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Table 2 Summary of GO analysis for D- and S-pair duplicates

From: Functional diversification of duplicate genes through subcellular adaptation of encoded proteins

  D-pair S-pair   
Biological process* No. Percentage No. Percentage P-value Excess
Biosynthetic process 32 21.1 111 42.9 0.0008 56
Catabolic process 32 21.1 17 6.6 0.0024 22
Regulation of biological process 59 38.8 56 21.6 0.0172 26
Response to biotic stimulus 0 0.0 12 4.6 0.1480 12
Nitrogen compound metabolic process 4 2.6 21 8.1 0.3988 14
Cell communication 18 11.8 15 5.8 0.4587 9
Primary metabolic process 110 72.4 210 81.1 0.5012 23
Cell cycle 21 13.8 20 7.7 0.5012 9
Response to endogenous stimulus 12 7.9 9 3.5 0.5012 7
Chemical homeostasis 0 0.0 6 2.3 0.5012 6
Cellular developmental process 11 7.2 9 3.5 0.5012 6
Chromosome segregation 5 3.3 2 0.8 0.5012 4
Cell division 21 13.8 25 9.7 0.6028 6
Response to stress 24 15.8 29 11.2 0.6483 7
Reproductive process 14 9.2 15 5.8 0.6696 5
Conjugation 7 4.6 6 2.3 0.6982 3
Sexual reproduction 7 4.6 6 2.3 0.6982 3
Aging 1 0.7 6 2.3 0.7084 4
Cellular metabolic process 120 79.0 214 82.6 0.7686 9
Asexual reproduction 3 2.0 2 0.8 0.7686 2
Nuclear division 1 0.7 0 0.0 0.7686 1
Protein localization 10 6.6 23 8.9 0.7785 6
Cell adhesion 0 0.0 2 0.8 0.7785 2
Response to chemical stimulus 17 11.2 25 9.7 0.8583 2
RNA localization 6 4.0 9 3.5 0.9959 1
Anatomical structure development 12 7.9 19 7.3 1 1
Establishment of localization 33 21.7 55 21.2 1 1
Macromolecule metabolic process 98 64.5 169 65.3 1 2
Response to external stimulus 0 0.0 1 0.4 1 1
Maintenance of localization 1 0.7 1 0.4 1 0
Response to abiotic stimulus 4 2.6 7 2.7 1 0
Cell organization and biogenesis 57 37.5 97 37.5 1 0
Regulation of biological quality 8 5.3 14 5.4 1 0
Autophagy 0 0.0 1 0.4 1 1
Filamentous growth 8 5.3 13 5.0 1 0
Cell homeostasis 7 4.6 12 4.6 1 0
Regulation of a molecular function 1 0.7 3 1.2 1 1
Cell proliferation 0 0.0 1 0.4 1 1
Non-developmental growth 1 0.7 2 0.8 1 0
  1. *We selected GO level 3, since this constitutes a good compromise between the number of genes annotated and the depth of the information contained in each class [46]. After false discovery rate correction. Represents the difference between the observed number of genes in the over-represented set and what would be expecated based on the observed genes in the other gene set.