Distribution of predicted NF-κB target genes. (a) The distribution of predicted NF-κB target genes in UM-SCC cells with different p53 status using five NF-κB binding PWMs. (b) The distribution of predicted genes regulated by RELA, NFκB1, or cREL using individual PWMs. (c) Comparison of distribution (%) of predicted genes by RELA, NFκB1, or cREL regulation in the up-regulated gene group of UM-SCC cells (left), and in the cells with wild-type p53-deficient status (right). §Statistical significance by chi square (X2, P < 0.001).