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Figure 2 | Genome Biology

Figure 2

From: Functionally important segments in proteins dissected using Gene Ontology and geometric clustering of peptide fragments

Figure 2

Figure depicting the concept of the GO directed acyclic graph for PDB entry 1woh. Each node is represented by a unique GO MF term (GO:0003674, molecular function; GO:0003824, catalytic activity; GO:0005488, binding; GO:0016787, hydrolase activity; GO:0016810, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0016813, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; GO:0019239, deaminase activity; GO:0043167, ion binding; GO:0043169, cation binding; GO:0046872, metal ion binding). The level of each GO term is indicated in the round text box. Note that the same GO term can have multiple levels depending on how you trace the path to the root GO term. The terms depicted in bold are annotated for the PDB in the GOA database [68]. A protein can be represented at various GO levels by taking the parent GO terms of the original PDB annotation.

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