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Figure 1 | Genome Biology

Figure 1

From: Gene expression-based screening for inhibitors of PDGFR signaling

Figure 1

PDGFR/ERK activation signature for high-throughput screening. (a) Genes whose expression is correlated with ERK activation by PDGFR. Genes (in rows) sorted by their expression in samples (columns) with or without U0126, apigenin, and PDGF. Red indicates high relative expression, blue low expression. (b) RT-PCR of signature genes in four sample wells: two lanes (replicas) per condition. TIP5 cells were serum starved overnight and then treated with PDGF. (c) Screening schema overview. SBE, single-base extension.

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