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Table 3 Prediction of number of transcripts per gene (synthetic data)

From: SPACE: an algorithm to predict and quantify alternatively spliced isoforms using microarrays

 

Number of transcripts

Gene name

1

2

3

4

5

6

CASP2

0%

100%

0%

0%

0%

0%

HNRPA2B1

0%

95%

5%

0%

0%

0%

BCL2L1

0%

90%

10%

0%

0%

0%

BIRC5

0%

0%

95%

5%

0%

0%

TERT

0%

0%

10%

85%

5%

0%

VEGF

0%

0%

0%

90%

10%

0%

BAX

0%

0%

20%

80%

0%

0%

WT1

0%

0%

100%

0%

0%

0%

  1. To apply NMF factorization, it is necessary to know, or estimate, the number of transcripts of a particular gene present in the samples under study. The estimations of the number of transcripts using SPACE for the genes used in the synthetic dataset are shown. Each entry of the table shows the proportion of predicted number of transcripts for different simulated data. The column corresponding to the real number of transcripts is shown in bold.