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Table 2 Summary of simulation results for 100 random genes (synthetic data)

From: SPACE: an algorithm to predict and quantify alternatively spliced isoforms using microarrays

Number of transcripts

MAE

Hamming distance

Sensitivity

Specificity

2

3.1%-4.6%-7.0%

0%-0%-0%

1 - 1 - 1

1 - 1 - 1

3

3.7%-5.1%-6.8%

0%-0%-0.85%

0.99 - 1 - 1

1 - 1 - 1

4

4.1%-5.2%-7.0%

0%-1.4%-2.9%

0.96 - 0.99 - 1

1 - 1 - 1

5

4.0%-5.4%-8.3%

1.5%-3.4%-9.6%

0.88 - 0.95 - 0.98

0.96 - 0.99 - 1

  1. The median value of MAE, Hamming distance, sensitivity and specificity for the simulation performed with 100 random genes is shown in bold for an equal number of transcripts. The variability of median values of each error measurement are indicated by the lower and upper quartiles at both sides of the median. It should be noted that the error increases as more transcripts are added to the simulation.