Figure 4

Variation in chromosomes 1, 5, and 13 for four serotype A strains. The DNA from the strains was hybridized to the array from the genome of strain H99, and gaps in the chromosomes represent the positions of repetitive sequences that represent putative centromeres or repeated elements in the MAT locus. The spikes in the Log2 ratios (for instance, for chromosome 1 of CBS7779) represent individual probes with high Log2 ratios (3 to 4); the sequences of these probes are present in single copy in the H99 genome but may be part of repetitive sequences in the other strains. For all of the chromosomes in all four strains, the hybridization data are shown in Additional data file 10, the Log2 ratios are listed in Table 1 and the regions of difference are listed in Additional data file 3.