Table 4 Transcription factors in the normal myeloid genetic network regulated by dysregulated transcription factors in APL
Differentially expressed TFs in APL | Regulated TFs in normal myeloid development | P value |
|---|---|---|
Arid5b | Rora | ~0 |
Arid5b | Tcf7 | 0.0019 |
Atf1 | Egr1 | ~0 |
Atf1 | Hlf | 0.0041 |
Atf1 | Rora | 0.0015 |
Atf1 | Smad7 | 0.0015 |
Fos | Egr2 | 0.0005 |
Fos | Rora | ~0 |
Fos | Tcf7 | 0.0036 |
Fos | Zfhx1a | 0.0005 |
Mybl2 | Rora | ~0 |
Rxra | Egr1 | 0.0003 |
Rxra | Etv4 | 0.0014 |
Stat5b | Foxo1 | 0.0005 |