Skip to main content
Figure 3 | Genome Biology

Figure 3

From: Computational identification of the normal and perturbed genetic networks involved in myeloid differentiation and acute promyelocytic leukemia

Figure 3

Predicted regulatory targets of Egr1 in myeloid differentiation. (a) Seven genes were identified as direct regulatory targets of Egr1. Three of these genes encode TFs (circle nodes). (b) Evolutionarily conserved Egr1 binding sites (red bars) were identified in the ± 2 kb proximal promoter region of the predicted target genes. All the Egr1 binding sites were conserved in human, mouse and rat except for PRDM16, whose rat ortholog was not available. Gene annotation information is color coded: blue, repetitive elements; yellow, conserved sequence; dark green, coding region; light green, untranslated region.

Back to article page

Genome Biology

ISSN: 1474-760X

Contact us