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Figure 5 | Genome Biology

Figure 5

From: Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes

Figure 5

Duplicated GRBs. Zebrafish HCNEs and their density distribution are shown for the human (a) PAX7 and (b) LHX1 loci. HCNEs are colored by the zebrafish chromosome they map to. In (a), most HCNEs are colored light green or gray and map to zebrafish chromosomes 11 or 23, respectively. In (b), most HCNEs are colored blue and map to zebrafish chromosome 15 (because this region contains many HCNEs, they are collapsed on a single row in this screenshot). The density plots are also separated based on zebrafish chromosomes. Comparison of synteny blocks to exon locations indicate that orthologs of AATF and ACACA are present next to the LHX1 ortholog (lhx1b) on zebrafish chromosome 5, but not on zebrafish chromosome 15 where lhx1a is located; this can be confirmed by detailed inspection of the zebrafish loci.

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