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Figure 4 | Genome Biology

Figure 4

From: Functional protein divergence in the evolution of Homo sapiens

Figure 4

Histogram distribution of CSs of orthologs for selected GO categories in M. musculus, D. rerio and D. melanogaster. (a) The CS distributions for proteins in three molecular function categories. 'Catalytic activity' is significantly conserved in all three organisms, while 'Transcription factors DBD' and 'Receptor activity' are significantly divergent in zebrafish and Drosophila. (b) The CS distributions for proteins in three biological process categories. 'Biosynthesis' is a highly conserved category in all three organisms, while 'Development' is significantly conserved in mouse but significantly divergent in Drosophila. 'Response to stimulus' is significantly divergent across all three organisms.

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