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Table 5 Intraspecific 5'~3' correlations of preference slopes for all 23 amino acid groupings

From: Finding exonic islands in a sea of non-coding sequence: splicing related constraints on protein composition and evolution are common in intron-rich genomes

   

SMA

 

Rho

P-value*

Slope (β)

Lower Cl†

Upper Cl†

Human

0.85

1.96E-06

1.04

0.83

1.29

Mouse

0.86

2.28E-06

0.99

0.80

1.23

D. rerio

0.66

8.3E-04

1.04

0.78

1.40

C. elegans

-0.14

0.52

-1.11

-0.73

-1.69

C. briggsae

-0.44

0.04

-0.75

-0.51

-1.09

A. gambiae

0.57

5.16E-03

1.08

0.79

1.48

D. melanogaster

0.61

2.49E-03

1.15

0.82

1.62

A. mellifera

0.39

0.06

1.32

0.88

1.96

A. thaliana

-0.22

0.30

NA‡

NA‡

NA‡

S. pombe

0.22

0.31

0.77

0.50

1.17

S. cerevisiae

0.16

0.46

2.42§

1.58

3.70

C. neoformans

0.02

0.92

NA‡

NA‡

NA‡

  1. *With 12 species significance is indicated by P = 0.05/12 = 4.17E-03. †CI = 0.95, the regression line was forced through the origin. ‡See Materials and methods. §Adequacy of SMA regression analysis is seriously in doubt for S. cerevisiae because normal distribution of residuals is strongly violated. NA, not available.