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Table 3 Amino acids significantly preferred (-) or avoided (+) at 3' (top rows) and 5' (bottom rows) exon ends of C. neoformans compared to human

From: Finding exonic islands in a sea of non-coding sequence: splicing related constraints on protein composition and evolution are common in intron-rich genomes

Amino acids*†  
A C D E F G H I K L4 L2 M N P Q R4 R2 S4 S2 T V W Y Species (number of exons)
+3   -7   -3    -2 -1   -5   -6 +2   +1 -4   +4      Human (178,438): 3'
  -6   +1 -2 +4 -7 -1 +3 -3      +6 -5 +2   +5     -4 C. neoformans (28,446): 3'
+2    -4 -5   +7 -3 -1   -2 -8 -6 +1 +4 +3 -7   +5 +6     Human (178438): 5'
  -9    -5 -7   -3    -1 -6   +2   +3 -4 +1    -8 -10 -2 C. neoformans (28,446): 5'
  1. *Indices signify rank order of slope coefficients, separately for negative and positive trends. L2, R2, S2 and L4, R4, S4 signify the two-fold and four-fold degenerate blocks of leucine, arginine, and serine, respectively.