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Table 3 Embryo dissections to determine time of death of homozygotes

From: A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development

  10.5 dpc 14.5 dpc 17.5/18.5 dpc
Name Normal Abnormal or resorbed Normal Abnormal or resorbed Normal Abnormal or resorbed
MommeD3    48 (60%) 32 (40%)*   
MommeD3 (F1)    80 (74%) 28 (26%)*   
MommeD5 35 (74%) 12 (26%)* 42 (72%) 16 (28%)*   
MommeD6 38 (63%) 22 (37%)* 25 (62.5%) 15 (37.5%)*   
MommeD7    44 (85%) 8 (15%)§ 63 (74%) 22 (26%)
MommeD8    101 (94%) 7 (6%)   
MommeD9 16 (64%) 9 (36%)* 19 (59%) 13 (41%)*   
MommeD10    54 (93%) 4 (7%) 86 (88%) 12 (12%)¥
Control cross 34 (94%) 2 (6%) 266 (93%) 19 (7%)   
  1. The abnormal embryos from which DNA could be extracted (17) were genotyped across the linked interval and all shown to be MommeD3-/-. These abnormal (very small) embryos were genotyped and shown to be MommeD5-/-. These normal embryos were genotyped and found to have the expected ratio of MommeD10+/+, MommeD10-/+ and MommeD10-/- embryos. ¥Four of the abnormal embryos were able to be genotyped: two were MommeD10-/+ and two were MommeD10-/-. *p < 0.0001; §p < 0.05.