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Table 3 Embryo dissections to determine time of death of homozygotes

From: A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development

 

10.5 dpc

14.5 dpc

17.5/18.5 dpc

Name

Normal

Abnormal or resorbed

Normal

Abnormal or resorbed

Normal

Abnormal or resorbed

MommeD3

  

48 (60%)

32 (40%)*

  

MommeD3 (F1)

  

80 (74%)

28 (26%)* †

  

MommeD5

35 (74%)

12 (26%)* ‡

42 (72%)

16 (28%)*

  

MommeD6

38 (63%)

22 (37%)*

25 (62.5%)

15 (37.5%)*

  

MommeD7

  

44 (85%)

8 (15%)§

63 (74%)

22 (26%)

MommeD8

  

101 (94%)

7 (6%)

  

MommeD9

16 (64%)

9 (36%)*

19 (59%)

13 (41%)*

  

MommeD10

  

54 (93%)

4 (7%)

86 (88%)¶

12 (12%)Â¥

Control cross

34 (94%)

2 (6%)

266 (93%)

19 (7%)

  
  1. †The abnormal embryos from which DNA could be extracted (17) were genotyped across the linked interval and all shown to be MommeD3-/-. ‡These abnormal (very small) embryos were genotyped and shown to be MommeD5-/-. ¶These normal embryos were genotyped and found to have the expected ratio of MommeD10+/+, MommeD10-/+ and MommeD10-/- embryos. ¥Four of the abnormal embryos were able to be genotyped: two were MommeD10-/+ and two were MommeD10-/-. *p < 0.0001; §p < 0.05.