Core promoters are predicted by their distinct physicochemical properties in the genome of Plasmodium falciparum

Table 3 MAPP performance by EGASP criteria

t	Sn₅₀	PPV₅₀	F₅₀	Sn₁₀₀	PPV₁₀₀	F₁₀₀
1.0	0.28	0.72	0.40	0.36	0.80	0.49
≥ 0.9	0.34	0.41	0.37	0.49	0.54	0.51
≥ 0.8	0.35	0.35	0.35	0.52	0.46	0.49
≥ 0.7	0.37	0.32	0.34	0.55	0.43	0.48
≥ 0.6	0.37	0.29	0.32	0.56	0.41	0.47
≥ 0.5	0.37	0.27	0.31	0.57	0.38	0.46
≥ 0.4	0.36	0.24	0.29	0.57	0.36	0.44
≥ 0.3	0.35	0.22	0.27	0.59	0.34	0.43

The performance of the MAPP was assessed using the criteria designed for the EGASP promoter prediction workshop. Each analysis was run with a TP window acceptance size (w) of ± 50 nucleotides or ± 100 nucleotides. t, MAPP score clustering threshold; PPV_w, positive predictive value; Sn_w, sensitivity; F_w, harmonic mean.

ISSN: 1474-760X