Figure 2

Evolutionarily conserved TDGs are enriched in developmental and transcription factor genes. The graph shows the ratio of the abundance of the listed GO categories in the different subsets of duplicated genes to the abundance among all duplicated genes. A value of 1 indicates that the abundance in a subset is comparable to that in the whole set. The conserved TDG subset is enriched in genes under the categories 'multicellular organismal developmental' and 'transcription factor activity'. p-values for individual children GO terms of these categories found to be overrepresented among conserved TDGs are all < 0.05 (Additional data file 5). Abbreviations: non TDGs, duplicated genes that are not arranged in tandem; TDGs, duplicated genes that are arranged in tandem; non cons TDGs, tandem duplicates that are not conserved in A. gambiae; cons TDGs, tandem duplicates that are conserved between D. melanogaster and A. gambiae.